Algorithms

Identification of Conserved Evolutionary Trajectories in Tumors

Pathway and network analysis of more than 2,500 whole cancer genomes

Combinatorial Detection of Conserved Alteration Patterns for Identifying Cancer Subnetworks

We introduce a novel combinatorial method, cd-CAP, for simultaneous detection of connected subnetworks of an interaction network where genes exhibit conserved alteration patterns across tumor samples.

HIT'nDRIVE: Patient-Specific Multi-Driver Gene Prioritization for Precision Oncology

An algorithm to identify cancer driver genes in individual cancer patients by measuring the influence of gene alterations on perturbing transcriptional networks.

HIT'nDRIVE: Multi-driver gene prioritization based on hitting time